#Bun creat ratio normal range full

It gives an accurate measure of the ability of your kidneys to remove the creatinine from your body. Creatinine ClearanceĬreatinine clearance is a measure of how much creatinine is in your urine. A creatinine level of greater than 1.2 for women and greater than 1.4 for men may be an early sign that the kidneys are not working properly.

As a result, creatinine is an indirect marker of glomerular filtration rate (GFR), or how well the kidneys work. If the kidneys lose their ability to filter blood (GFR decreases), more creatinine will accumulate and serum creatinine will rise. When the kidneys are not working well, creatinine builds up in the blood. Healthy kidneys take creatinine out of the blood and remove it from the body through the urine. Serum CreatinineĬreatinine is a waste product in the blood created by the normal metabolism of muscle cells. Other possible causes of an elevated BUN include dehydration and heart failure.

#Bun creat ratio normal range full

If your BUN is more than 20 mg/dL, your kidneys may not be working at full strength. Normal blood contains 7-20 mg/dl of urea. If your kidneys are not working well, the urea nitrogen will stay in the blood. Healthy kidneys take urea nitrogen out of the blood and remove it through the urine.

After the cells use the protein, the remaining waste product is returned to the blood as urea nitrogen. Blood Urea Nitrogen (also called BUN)īlood carries protein to cells throughout the body. Note that there can be some differences in these values from one lab to another, so make sure you learn the normal values for your lab. The test results will be used to assist the healthcare team (your doctor, nurses, and others) in evaluating your kidney function and determining the best care plan for you.Remember, you are in control and you are your own best healthcare advocate, so it is essential for you to understand what these tests mean. Lab work, urine samples, and other tests may be completed as you undergo diagnosis and treatment for renal failure. CLINICAL TRIALS: gov identifier NCT00328692 and NCT00354458.Common Tests to Help Diagnose Kidney Disease CONCLUSIONS: In patients with AHF, BUN/creatinine higher than age-specific and sex-specific normal range is associated with worse prognosis independently from both creatinine and BUN. In Cox regression analysis, higher than normal range of BUN/creatinine ratio group was an independent predictor for all-cause death (HR: 1.86, 95% CI 1.29 to 2.66) and death or cardiovascular or renal rehospitalisation (HR: 1.37, 95% CI 1.03 to 1.82), but not for HF rehospitalisation (HR: 1.23, 95% CI 0.81 to 1.86) after adjustment for other prognostic factors including both creatinine and BUN. RESULTS: In a cohort of patients with AHF, 482 (24.6%) and 28 (1.4%) patients with HF were classified into higher and lower than normal range groups, respectively. Association of abnormal range to prognosis was tested in 2033 patients with AHF for the outcome of all-cause death through 180 days, death or cardiovascular or renal rehospitalisation through 60 days and heart failure (HF) rehospitalisation within 60 days. METHODS: In 4484 subjects from the general population without cardiovascular comorbidities, we calculated age-specific and sex-specific normal values of the BUN/creatinine ratio, deriving a higher and lower than normal range of BUN/creatinine ratio (exceeding the 95% prediction intervals). The aim of this study is to define the normal range of BUN/creatinine ratio and to investigate its clinical significance in patients with AHF. OBJECTIVE: The blood urea nitrogen-to-creatinine (BUN/creatinine) ratio has been proposed as a useful parameter in acute heart failure (AHF), but data on the normal range and the added value of the ratio compared with its separate components in patients with AHF are lacking.